News Publications Archive RESprotect Publications Prevention of adriamycin-induced mdrl gene amplification and expression | Prevention of adriamycin-induced mdrl gene amplification and expression |
|
|
|
Page 7 of 7
AcknowledgementsWe thank Dr. H.-D. Zucht (Niedersächsisches Institut für Peptid-Forschung, Hannover/Germany) for his help in measuring gene amplification. (E)-5-(2-bromovinyl)-2´-deoxyuridine (BVDU) was a gift from Berlin-Chemie/Berlin/Germany. Friend mouse erythroleukemia cells, line F4-6 were kindly provided by Prof. W. Ostertag (Heinrich Pette Institute/Hamburg/Germany). The mdr1 probe pHDR5A was generously provided by Dr. M. M. Gottesman, National Cancer Institute, NIH, Bethesda, Md., USA; the human b-actin cDNA probe was kindly provided by Dr. T. Braun, Institute of Biochemistry and Biotechnology, University of Braunschweig, Germany).
ReferencesBhushan,A., Abramson,R., Chiu,J.F. & Tritton,T.R. (1992) Expression of c-fos in human and murine multidrug-resistant cells. Mol. Pharmacol., 42, 69-74. Bhushan,A., Slapak,C.A., Levy,S.B. & Tritton,T.R. (1996) Expression of c-fos precedes MDR3 in vincristine and adriamycin selected multidrug resitant murine erythroleukemia cells. Biochem. Biophys. Res. Commun., 226, 819-822.
Bordow,S.B., Haber,M., Madafiglio,J., Cheung,B., Marshall,G.M. &
Norris, M.D. (1994)
Expression of the multidrug resistance-associated protein (MRP) gene correlates
with amplification and overexpression of the N-myc oncogene in childhood
neuroblastoma. Cancer Res., 54, 5036-5040. Chomczynski,P. & Sacchi,N. (1987) Single-step method of DNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159. Demidova,N.S., Goncharova,S.A., Chernova,O.B., Kopnin,B.P. & Gudkov,A.V. (1987) Gene amplification in murine leukemia cells with multiple drug resistance acquired in vivo. Genetika, 23, 1797-1806. Fahrig,R. (1996) Anti-recombinogenic and convertible co-mutagenic effects of (E)-5-(2-bromovinyl)-2’-deoxyuridine (BVDU) and other 5-substituted pyrimidine nucleoside analogs in S. cerevisiae MP1, Mutation Res., 372, 133-319. Fahrig,R. & Steinkamp-Zucht,A. 1996) Induction or suppression of SV40 amplification by genotoxic carcinogens, non-genotoxic carcinogens or tumor promoters, Mutation Res., 356, 217-224. Ford,J.M. & Hait,W.N.(1990) Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol. Rev., 42, 155-199. Frye,R.A., Benz,C.C. & Edison,L. (1989) Detection of amplified oncogenes by differential polymerase chain reaction. Oncogene, 4, 1153-1157. GottesmannM.M. (1993) How cancer cells evade chemotherapy: sixteenth Richard and Hinda Rosenthal foundation award. Cancer Res., 53, 747-754. Gudkov,A.V., Chernova,O.B. & Kopnin,B.P.(1991) Karyotype and amplicon evolution during stepwise development of multidrug resistance in Djungarian hamster cell lines, in: I. B. Roninson (ed.), Molecular and cellular biology of multidrug resistance in tumor cells, Plenum, New York; p. 147-168. Haynes,R.H. (1985) Molecular mechanisms in genetic stability and change: The role of deoxyribonucleotide pool balance, in: F.J. de Serres (Ed.), Genetic Consequences of Nucleotide Pool Imbalance, Plenum, New York. p. 1-23. Hsu,S.I.-H., Lothstein,L. & Horwitz,S.B. (1989) Differential overexpression of the mdr genes family members in multidrug-resistant J 774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes. J. Biol. Chem., 264, 12053-12062. Hsu,S.I.-H., Cohen,D., Kirschner,L.S., Lothstein,L., Hartstein,M. & Horwitz,S.B. (1990) Structural analysis of the mouse mdr1a (P- glycoprotein) promoter reveals the basis of differential transcript heterogeneity in multidrug-resistant J 774.2 cells. Mol. Cell Biol., 10, 3596-3606.
Kunz,B.A., Kohalmi,S.E., Kunkel,T.A., Mathews,C.K., McIntosh,E.M. &
Reidy,J.A. (1994) Deoxyribonucleoside
triphosphate levels: A critical factor in the maintenance of genetic stability.
Mutation Res., 318, 1-64.
Nakagawara,A., Kadomatsu,K., Shin-ichi,S., Kohno,K., Akazawa,.K, Nose,Y.
& Kuwano,M.(1990) Inverse
correlation between expression of multidrug resistance gene and N-myc oncogene in human neuroblastomas. Cancer Res., 50, 3043-3047. Norris,M.D., Bordow,S.B., Marshall,G.M., Haber,P.S., Cohn,S.L. & Haber,M.(1996) Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma. N. Engl. J. Med., 334, 231-238. Ostertag,W., von Ehrenstein,G. & Charache,S. (1972) Duplicated-chain genes in Hopkins - 2 haemoglobin of man and evidence for unequal crossing over between them. Nature New Biol., 237, 90-94. Schaefer,A., Westendorf,J., Lingelbach,K., Schmidt,C.A., Mihalache,D.-L., Reymann, A. & Marquardt,H. (1993) Decreased resistance to N,N-dimethylated anthracyclines in multidrug-resistant Friend erythroleukemia cells. Cancer Chemoter. Pharmacol., 31, 301-307. Schimke,R.T., Sherwood,S.W., Hill,A.B. & Johnston,R.N. (1986) Overreplication and recombination of DNA in higher eukaryotes: potential consequences and biological implications. Proc. Natl. Acad. Sci., USA, 83, 2157-2161. Volkert,J.R. (1986) Site-specific recombination promotes plasmid amplification in yeast.Cell, 46, 541-550.
Volm,M., Mattern,J. & Pommerenke,E.W. (1991) Time course
of mdr gene amplification during in vivo selection for
adriamycin-resistance and during reversal in murine leukemia L 1210. Anticancer Res., 11, 579-586. Wahl,G.M. (1989) The importance of circular DNA in mammalian gene amplification. Cancer Res., 49, 1333-1340. Winkelmeier,P., Glauner,B. & Lindl,T. (1993) Quantification of cytotoxicity by cell volume and cell proliferation. ALTERNATIVES TO LABORATORY ANIMALS: ATLA, 21, 269.
|
|||||||||